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GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer
In men, reduced inflammation could aid sperm health but not change seminal protein composition that governs post-ejaculation function
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We have recently shown that the collateral sensitivity of resistant cells to these drugs is dependent on P-gp expression and activity, whereby stimulation of its ATPase activity triggers a rise in reactive oxygen species (ROS) leading to heightened oxidative cell death of resistance cells [14,15,16,17]
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