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Glutathione is crucial for maintaining the health of red blood cells, which are essential for oxygen transport and energy production
Soule S, King JA, Millar RP
Free Radical Res 55(1112):10481061 Lei L, Zhang F, Huang J, Yang X, Zhou X, Yan H, Chen C, Zheng S, Si L, Jose PA, Zeng C (2023) Selenium deficiency causes hypertension by increasing renal AT1 receptor expression via GPx1/H2O2/NF-B pathway
In summary, these data provide evidence that long-term IGF-1R blockade with mAbs is feasible, well tolerated, and can recapitulate effects observed with genetic disruption of IGF-1R signaling on lifespan
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