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in the latter, proopiomelanocortin (POMC) neurons are present and it is believed that endogenous GLP-1 induces satiety, affecting both anorexigenic and orexigenic signaling pathways

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Clinical relevance [edit] Disease association [edit] Genetic activation of NRF2 has been implicated in the development of de novo tumors, [40] [41] as well as in the progression of atherosclerosis by increasing plasma cholesterol levels and hepatic cholesterol content