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Description

Tesofensine is characterised in the literature as acting across three monoamine transporter systems serotonin (SERT), noradrenaline (NET) and dopamine (DAT)

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This mechanism explains how small-molecule inhibitors, such as statins, can inhibit YAP/TAZ nuclear localization and transcriptional functions (56)

Mutants that are impaired in glutathione biosynthesis exhibited a stronger growth inhibition than WT seedlings when exposed to AITC, independent of whether the mutation was present in the first or second enzyme of glutathione biosynthesis (Figs 2 and 3)