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Notably, AcM concentration also led to a decreased ability of the caecal microbiota to generate energy through functions such as glycolysis and to a reduction in the metabolism of ribosomal protein and nucleotides, together with a depletion of DNA homologous recombination, replication, and mismatch repair
In parallel, we observed distinct effects on DMD and AME, with significant improvements observed primarily at 300 mg/Kg of AcM (T3) and to a lesser extent with T4 only for AME, while a decrease was noted in T2
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