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10.1111/j.1538-7836.2007.02709.x 40 DeanW

That uncertainty is precisely why it remains an interesting research tool rather than a settled one, and it is stated plainly here rather than papered over with confident mechanism claims

Functional activation of DCs stimulates NK-cells, promotes an increase in proinflammatory cytokines (IL-12, IL-6, IL-23, IL-1) and a decrease in antiinflammatory transforming growth factor- (TGF-1), which control adaptive reactions, which contributes development of Th1 and Th17, IL-17-producing T cells and cytotoxic T cells