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Passage of bile acids through the enterocyte activates FXR, which promotes the synthesis of fibroblast growth factor 19 (FGF19), which also circulates through the portal vein to the liver where it activates fibroblast growth factor-receptor 4 resulting in inhibition of bile acid synthesis
Users documenting before-and-after progress often report remarkable clarity and radiance within a few sessions
The difference in efficacy between these two doses is modest, but the difference in side effects can be meaningful for some individuals