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226 It is activated through two major branches, the canonical (IB-dependent) and noncanonical (NIK-dependent) pathways, both of which are frequently dysregulated in tumors and their microenvironments
Blood tests may include HbA1c or fasting glucose (diabetes screening), lipid profile (cardiovascular risk), and early-morning total testosterone levels (usually measured between 911 am and repeated if low)
Stable medication protocols are generally preferred during periods of hormonal transition
But, similar to cancer, there are no randomised human trials
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