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Studies have shown that Erastin can also modulate p53 signaling outside its canonical ferroptosis activity, altering transcriptional programs that regulate cell-cycle progression and stress responses and thereby intensifying cytotoxicity in sensitive tissues (96)

The experience, which from the outset as a chosen treatment to enhance well-being rather than a treatment for illness was, as one would hope, perfect

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During the week before the experiments began, all mice were housed under conventional conditions and fed a standard diet and water ad libitum at the animal facility (Research Resource Facility)