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Los pacientes que presenten signos clnicos de gravedad o compatibles con proceso tumoral y los recin nacidos en los que la hepatomegalia se acompae de colestasis, deben ser remitidos a un centro hospitalario, con el fin de agilizar el diagnstico y el tratamiento
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Because fasting is a primary trigger for life-threatening metabolic crises in SPCD [3] , it is absolutely critical to get specific, age-stratified fasting guidelines directly from a metabolic geneticist
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