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AC system activation generates an increase of the intracellular secondary messenger, cyclic adenosine monophosphate (cAMP), through the conversion of adenosine triphosphate, which then results in the activation of protein kinase A (PKA) and exchange protein activated by cAMP (Epac) [32,33,34,35]

Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis [PMID: 19661458] Laboratory literature summary: Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes

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2014, Feb;35(7):238390