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70 Use of activated charcoal is not without risks, however, and one must be wary of aspiration pneumonia, vomiting, diarrhea, constipation, ileus, and interference with the patients regular medications
The downregulation of SGK1 expression leads to decreased phosphorylation and the increased stability of the transcription factor forkhead box O 3a (FOXO3a), which activates the expression of bcl2/adenovirus e1b-interacting protein 3 (BNIP3), an inducer of autophagy through interactions with LC3 (Wu et al., 2023)