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However, the TME is complex, including not only various immune cells but also cellular and non-cellular components such as mesenchymal cells, blood vessels, lymphatic vessels, and cytokines (245), therefore, it is also possible that nanoparticles that exert anti-tumor effects by modulating other components

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Deficiency in epithelium RAD50 aggravates UC via IL-6-mediated JAK1/2-STAT3 signaling and promotes development of colitis-associated cancer in mice