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A Phase 2 RCT published in NEJM 2023 reported a mean body weight reduction of approximately 24% at 48 weeks with the 12 mg weekly dose in adults with obesity
Horm Res 46:174182 Molitch ME, Clemmons DR, Malozowski S, et al
For this purpose, the adjunctive therapeutic use of small molecules that either inhibit or stimulate eryptosis could represent a valid strategy for the treatment or prevention of pathological complications associated with erythrocyte dysfunction
Maintaining adequate nutrition and exercise, including appropriate protein intake and resistance training, can help prevent loss of strength in most patients
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