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Does a change in the total cellular GSSG/GSH ratio ultimately change that ratio in the ER, or does GSSG exert its effects on the ER environment indirectly
Moreover, it was reported that supplementing the diet with the antioxidants N -acetylcysteine and vitamin E markedly increases tumor progression and reduces survival in mouse models of B-RAF- and K-RAS-induced lung cancer, by reduction of ROS, DNA damage, and p53 expression (Sayin et al., 2014)
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Because they may shield the stomach lining and lessen inflammation in the digestive tract, several peptides, such as BPC-157, are also being researched for gut health
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