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PubMed Systematic reviewGLP-1 class evidence2025 Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition Supports body-composition, lean-mass, and metabolic-risk context
Since the drugs help people lose weight, it wasnt surprising that they would deliver additional health gains
As predicted by trRosetta, the fusion of HSA-binding DARPin to GLP-1 using a rigid helical linker does not alter the tertiary structure of the fusion partner, and each moiety of the fusion proteins will most likely retain their conformational properties and relevant biological functions as the native protein
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