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Weight Loss Patient "The testosterone therapy has been a game changer

This comes down to managing side effects rather than its overall effectiveness

The FDA also recommends examining hard clinical endpoints such hepatic decompensations, transplant free survival, and all-cause mortality, although these results are not necessarily needed prior to drug approval given the long length of follow up potentially required

If tolerability issues arise with the combination, healthcare providers might consider temporarily pausing dose escalation, using 1.7 mg as a maintenance dose if 2.4 mg is not tolerated, adjusting Prozac timing (e.g., taking with food), or implementing supportive measures