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Semaglutide (a GLP-1 agonist) has been demonstrated to result in notable weight loss
Moreover, this comprehensive structural biophysical analysis [50] also identified two hydrogen bonds the binding interface of semaglutide and GLP-1R ECD [29, 52], as listed in Table 2
This novel dual-agonist approach surpassed the efficacy of monotherapy while maintaining a favorable costbenefit and safety profile [122]
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