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Commun Biol 9 , 25 (2026)

Also seek emergency care for: Persistent vomiting that prevents you from keeping down fluids or medications Signs of dehydration (decreased urination, extreme thirst, dizziness) Vomiting blood Severe upper right abdominal pain, fever, or yellowing of skin/eyes (possible gallbladder disease) Progressive abdominal distension with inability to pass gas or stool (possible intestinal obstruction) Contact your healthcare provider within 24-48 hours if you experience persistent nausea or vomiting lasting more than a few days, as this may require dose adjustment or additional management strategies

6 Neurohormonal Mechanisms GLP-1RAs may modulate the activity of the autonomic nervous system by shifting the balance away from sympathetic overactivation towards parasympathetic tone

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