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Furthermore, clinically attainable concentrations of PAC have been shown to decrease in vitro intracellular GSH in human pulmonary macrophages, type II pneumocytes, and lymphocytes (Estvez et al., 1994
The trade-off is that the carrier is a large addition to the matrix: it changes the background in protein assays, interferes with some analytical methods, and introduces its own lot-to-lot variability
The compound reduces hematocrit and hemoglobin levels, probably by inducing oxidative stress in erythrocytes
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