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Notably, deletion of the equilibrative nucleoside transporter 1 (ENT1) leads to reduced AQP4 expression, further linking purinergic signaling to astrocytic water channel regulation [422]
Nutrients, 12 (10), 3209
Owing to recent technological advances, including the application of scRNAseq and spatial transcriptomics to mouse models, we now know that the population of EmKCs is depleted during MASLD development and is replaced by distinct subsets of bone marrow-derived macrophages [29, 46]
Here is what patterns emerge from various sources
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