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The healing occurred regardless of administration route
This may make them more easily triggered when estrogen levels are high or when estrogen levels fluctuate (menstrual changes or perimenopause)
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These nanocarrier platforms are not merely vehicles for drug transport but are sophisticated, multifunctional systems engineered to overcome each of the biological and pharmacological barriers that limit free drug performance, and their design is guided by four interdependent principles that collectively define the modern standard for rational nanomedicine development [68]
