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However, it maintains the dose-dependent cortisol/prolactin increase: around +20-40% cortisol and +15-30% prolactin depending on the dose range

doi:10.3390/ijms23158727

It's also common to lose some muscle mass along with fat while on these drugs, which can be problematic, Kessler writes

It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells