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Hydroxocobalamin is preferred because it binds more tightly to serum proteins, creating a depot effect that allows slower release and longer duration of action
Likewise, the combination of pentoxifylline and angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) reduced proteinuria by ameliorating the decline in eGFR in patients with stages 35 CKD [150]
Eur Neuropsychopharmacol
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