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Studies in older mice investigating individual cells as well as larger vessels and micro-vessels will be useful in determining which cells of the cerebrovasculature are responsible for these changes and whether there are APOE -driven differences in FAO in both larger and smaller vessels that can affect transport functions
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The identification of GLP-1R in other regions of the CNS provided a further advance in the understanding of the role played by GLP-1/serotonin cross-talk in the regulation of homeostatic control of body mass
It is also not for type 1 diabetes
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