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Effects were most pronounced in patients who were extensive cytochrome P450 (CYP) 2D6 metabolizers
It may develop secondarily to HIV-induced cytokine dysregulation, to medications used in the treatment of HIV infection or HIV-associated diseases (zidovudine, clofazimine and ketoconazole), or to adrenocortical deficiency, which is not infrequent in HIV-seropositive subjects with a low CD4+ T cell counts [6, 10]
185, no
Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs
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