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SITAGLIPTIN PHOSPHATE + METFORMIN HCl (JANUMET) treatment should not be initiated in patients 80 years of age unless measurement of creatinine clearance demonstrates that renal function is not reduced (see Metformin hydrochloride under Precautions)
Diabetes Care 44:826835
Zehetner about treating reflux using GLP-1 agonists, which mimic the bodys own GLP-1 hormone
For example, in some large-scale studies, participants taking the highest dose of tirzepatide (15 mg) lost an average of 20% or more of their body weight over 72 weeks
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