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The reverse cholesterol transport (RCT) pathway involving high-density lipoprotein (HDL) is an important process to maintain the balance of cholesterol metabolism, and promotes the efflux of free cholesterol from macrophages (63)

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That difference matters, and it shapes the kind of before and after results you can reasonably expect

Additionally, patients experiencing significant nausea may eat less frequently or consume smaller portions, potentially leading to inadequate caloric intake or skipped meals, both of which are well-established headache triggers