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GLP-1 agonists work by mimicking the action of naturally occurring GLP-1, an incretin hormone released from the intestinal L-cells in response to food intake
The typical dosage for horses is 5-10ml per 100lbs of body weight, administered by subcutaneous or intramuscular injection
Because it escapes binding to these inhibitory proteins, IGF-1 LR3 remains free in experimental environments to interact continuously with the IGF-1 receptor, resulting in an extended biological half-life and vastly increased potency compared to standard IGF-1
Long-Smith CM, Manning S, McClean PL, Coakley MF, OHalloran DJ, Holscher C, et al
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