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& Yodoi, J
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The UPR is initiated through three sensors: the protein kinase RNA-like ER kinase (PERK), the inositol requiring enzyme-1 (IRE-1), and the activating transcription factor-6 (ATF-6)
11d and 11g) Given the differentiation in conformational dynamics of Cagri-bound versus rAmy-bound to CTR or AMYRs and the likely role that the P37 Cagri played in these differences, we also assessed in the assay an analogue of Cagri that contained a P37Y substitution
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