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Immune Component Impact on BBB Integrity In inflammatory states, endothelial cell expression of TJs proteins decreases and adhesion molecule expression increases (De Laere et al., 2020) or by serum from patients with breast cancer and brain metastasis tested on CD34 + -derived endothelial cells (Curtaz et al., 2020)
Common side effects like nausea, vomiting, diarrhea, and other more serious side effects like pancreatitis and thyroid C-cell tumors are included among the official documentation
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VMAT2 imaging using 11 C-DTBZ or 18 F-FP-DTBZ reflects monoaminergic terminal integrity and correlates with disease severity [138]
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