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Compared to the control, T2DM patients treated with semaglutide 1 mg saw a reduction of 29 mg/dL (22%) for pre-prandial glucose, 74 mg/dL (36%) for 2-h postprandial glucose, and 30 mg/dL (22%) for mean 24-h glucose concentration [26]
In the gastrointestinal tract, GLP-1 delays gastric emptying through vagal activation and effects on smooth muscle, increases beta cell proliferation and survival as well as glucose-dependent insulin secretion, suppresses glucagon secretion, and reduces hepatic fat accumulation through fatty acid oxidation as well as hepatic gluconeogenesis [43]
Around Week 12: Body Composition The twelve-week mark is when measurable changes in body composition typically emerge: increased lean muscle mass, a decrease in visceral fat, and visible changes to waist circumference and overall shape
I also had to remind myself frequently that strength training was adding muscle tone, and the scale might not be my best friend, Haynes-Ferere says
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