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Important context: SURMOUNT-5 was an open-label trial funded by Eli Lilly, the manufacturer of tirzepatide
These are powerful compounds, he said
Inhibitory KORD-DREADD expression in the OB resulted in increased chow intake in RD mice, whereas excitatory hM3Dq-DREADD induced a decreased chow and high-fat high-sucrose diet in WD mice
In appropriate patients, treatment may contribute to lowering the risk of major cardiovascular events
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