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The two peptides activate different receptors on pituitary somatotroph cells: the CJC-1295 acts via the GHRH-R and theIpamorelin via GHS-R1a
Peptides are short chains of amino acids that help regulate functions such as metabolism, growth and tissue repair, according to Cleveland Clinic
It has completed Phase 3 clinical trials (the REDEFINE program) with positive results, and Novo Nordisk is expected to seek FDA approval
More serious but rare adverse effects include pancreatitis, gallbladder disease, and potential thyroid concerns (based on animal studies, though human risk remains unclear)
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