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When unmanaged, these symptoms can undermine the full potential benefits of GLP-1 receptor agonists like semaglutide or tirzepatide

Amputation only BPC 157 (10 g/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg), given alone or combined, were applied intraperitoneally, at 30 minutes before amputation while controls received simultaneously an equivolume of saline (5ml/kg intraperitoneally)

By synthesizing these aspects, this review aims to provide insights for a deeper understanding of the relationship between ferroptosis and DR, as well as potential prevention and treatment strategies

Sander AL, Lehnert T, El Saman A, Eichler K, Marzi I, Laurer H