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This finding is provocative but not directly confirmed in humans
is a Medical Research Council Clinical Doctoral Training Fellow (MR/V028723/1)
Methodologically, we outline how single-cell and spatial multi-omics, imaging mass spectrometry and functional biosensors now enable co-registration of metabolite exposure with immune-cell states in human tumors, providing an actionable basis for biomarker discovery
GLP-1 therapies are reshaping healthcare, and understanding their impact is critical for individuals, industries, and public health
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