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doi:10.1007/s00441-019-03016-8 Mayfield CK, Bolia IK, Feingold CL, et al
Because cagrilintide is typically used at very low concentrations in assay systems, solubility at the working concentration is rarely a limiting factor even without special solvents
To counteract amyloid fibril formation that occurs with human Amy, a pair of helix-stabilizing mutations (N14E and V17R) were incorporated into Cagri 2
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