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Description

These medications are typically administered once or twice daily and are largely eliminated from the system within 24 hours

Brayden DJ, Gleeson J, Walsh EG

The peptide incorporates a C20 fatty diacid moiety via a Glu-Glu linker enabling reversible albumin binding and an extended pharmacokinetic profile compatible with once-weekly dosing

#MedicinalChemistry #ReceptorPharmacology #SAR #DrugDiscovery #ClinicalPharmacy To view or add a comment, sign in Meet GLP-1 a hormone with a short half-life and a disproportionate role in metabolic biology