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The glucagon receptor agonism, whilst counterintuitive given glucagon's role in raising blood glucose, is thought to increase energy expenditure and promote hepatic fat oxidation whilst reducing lipogenesis effects that may offer potential benefits in metabolic dysfunction-associated steatotic liver disease (MASLD)

Figure 5 shows that four subjects (15.1%) with weakness were improved in L-carnitine group, while no improvement was found in the placebo group

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In female patients, menstrual problems and issues with repeated miscarriage have been reported[11]