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The resulting increase in intracellular NAD+ availability activates sirtuins particularly SIRT1, which regulates insulin sensitivity, gluconeogenesis, cholesterol synthesis, and fatty acid oxidation, and SIRT3, which governs mitochondrial antioxidant defences and energy metabolism
So, AOD 9604 should be viewed as a tool for studying metabolism, not as a weight loss treatment
Research shows this dose works well to fix deficiency and reduce symptoms like tiredness, weakness, and nerve problems
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