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Some research suggests it may influence glucose metabolism, lipid profiles, and gut microbiota composition, though evidence quality varies

While the data is promising, its still early

Many clinicians suggest approximately 1.2 to 1.6 grams of protein per kilogram of body weight daily to minimize lean tissue loss during semaglutide treatment, though requirements should be individualized with healthcare provider guidance based on kidney function and other health conditions

As expected, a 12-week course of HFD feeding induced early-stage liver pathologies of NAFLD in mice including fatty liver and liver injury, which were manifested by increased hepatic TG levels (Fig