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Clinical trials show it can lead to significant weight loss when used alongside gentle changes to food and movement (Koman et al., 2024)
Its important to note that semaglutide is not intended to be a standalone treatment
Food is less relevant as a source of comfort or craving
Amino acids 130 and 3160 constitute two copies of modified human GLP-1, the alanine at position 2 having been exchanged for a glycine for better DPP-4 resistance
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