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Among GLP-1RAs, Semaglutide was the most cost-effective obesity medication [59] [60]
This prolongs and amplifies the physiologic effects of endogenous GLP-1
We also know that high levels of human growth hormone over a long period can produce irreversible acromegaly, the complications of which include arthritis, sleep apnoea, diabetes, high blood pressure, heart disease and often premature death
It is understood that complications due to aggressive host immune responsesuch as dramatic apoptosis as a result of fulminant inflammation in lungs and other organsmay prove challenging in COVID-19 infections [30, 71]
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