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Even if semaglutide is not officially approved for COPD, doctors might still prescribe it off-label to COPD patients who also struggle with obesity

Biologic complexity: Unlike small-molecule drugs, semaglutide is a biologic, meaning any generic version would likely be a biosimilar, which involves a more complicated manufacturing process that is highly regulated and more expensive than manufacturing generic drugs

Originally, GLP-1 receptor agonists were actually designed as a treatment for diabetes, alongside the medication metformin

3-5 GLP-1 drugs work by attaching to special spots in the brain called GLP-1 receptors