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10.1111/bcpt.70021 Basic Clin Pharmacol Toxicol
The therapeutic landscape for GPCR as targets of anti-obesity medications has undergone significant changes with the approval of semaglutide, the first peptide glucagon like peptide 1 receptor agonist (GLP-1RA) achieving double digit weight loss (10%) and cardiovascular benefits
The GLP-1 based therapies led to statistically significant reductions in the serum levels of some atherosclerosis markers
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