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Vegetables: Zucchini, bell peppers, carrots, spinach, lettuce, tomatoes, and green beans are generally well-tolerated

Buse et al

Weeks 13 through 16: increase to 10mg The 10mg dose represents a significant jump in therapeutic effect

This leads to increased bile acids in the intestinal lumen, which then trigger Takeda G-protein-coupled receptor 5 (TGR5) on L-cells, stimulating the production and release of GLP-1 (Thomas et al., 2009