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Using advanced tracer methodologies, the researchers identified a fascinating metabolic phenomenon they termed "brain glucose steal." Due to systemic mitochondrial impairment, non-brain organs were essentially stealing glucose intended for the central nervous system, starving the brain of energy and driving cognitive dysfunction
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Cagrilintide at 2.4 mg produced nausea in approximately 55% of REDEFINE trial participants, though this was predominantly mild and transient
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