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doi: 10.3389/fimmu.2023.1303921 Received 28 September 2023 Accepted 13 November 2023 Published 29 November 2023 Volume 14 - 2023 Edited by Heiko Mhl, Goethe University Frankfurt, Germany Reviewed by Yankai Wen, University of Texas Health Science Center at Houston, United States
Intracellular ROS are mainly produced by the electron transport chain of mitochondria and NADPH oxidase ( 2 ), hydrogen peroxide (H 2 O 2 ), hydroxyl radicals, and oxygen anions (Shadel and Horvath, 2015)
Immediately prior to experimentation, the stock solution was diluted with sterile saline to a concentration of 50 mg/kg (final DMSO concentration 1%) 31,32
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