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RGNEF4 aids in Ca2+ release via IP3 as well as the Diacylglycerol (DAG) pathway by activating Phospholipase C
Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism (Mari et al., 2013)
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