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"The immune response in autism: a new frontier for autism research"

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Oxidative stress may also down-regulate other essential enzyme systems associated with the methionine cycle, including methionine synthase, betaine-homocysteine methyltransferase and methionine adenosyltransferase, leading to further monoamine neurotransmitter disruption and weakening of antioxidant enzyme activities (Guildford)

309 In rehabilitation, combining physical therapy with molecular and genetic insights can accelerate recovery and improve outcomes